Harshani R Lawrence Selected Research

2- ethyl- 16- ((3- pyridylmethylamino)carbonylmethyl)estrone

5/2008

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

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Harshani R Lawrence Research Topics

Disease

27	Neoplasms (Cancer) 01/2022 - 05/2007
9	Breast Neoplasms (Breast Cancer) 10/2014 - 02/2006
6	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 06/2012
3	Melanoma (Melanoma, Malignant) 01/2020 - 07/2012
3	Carcinogenesis 10/2019 - 03/2015
3	Pancreatic Neoplasms (Pancreatic Cancer) 05/2019 - 04/2012
3	Lung Neoplasms (Lung Cancer) 01/2019 - 02/2014
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2022 - 01/2019
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2020 - 11/2017
2	Hematologic Neoplasms (Hematological Malignancy) 01/2017 - 04/2014
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2022
1	Rheumatoid Arthritis 01/2021
1	Hyperplasia 01/2018
1	Multiple Myeloma 04/2014
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2014
1	Adenocarcinoma 01/2013
1	Leukemia 09/2010
1	Choriocarcinoma 03/2006

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 12/2018 - 05/2008
6	Phosphotransferases (Kinase)IBA 01/2019 - 05/2014
6	Hormones (Hormone)IBA 03/2015 - 02/2006
4	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 06/2012
3	Antineoplastic Agents (Antineoplastics)IBA 01/2022 - 04/2014
3	Messenger RNA (mRNA)IBA 12/2018 - 03/2006
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2015 - 04/2012
2	enzalutamideIBA 01/2022 - 12/2017
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 12/2016
2	AndrogensIBA 01/2018 - 06/2012
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018 - 02/2014
2	Histones (Histone)IBA 12/2017 - 05/2014
2	AIM-100IBA 10/2014 - 06/2012
2	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2014 - 03/2012
2	Proteasome InhibitorsIBA 04/2014 - 08/2010
2	SurvivinIBA 03/2013 - 05/2007
2	Cyclin D1IBA 03/2013 - 05/2007
2	Small Interfering RNA (siRNA)IBA 01/2013 - 05/2008
2	Protein Tyrosine PhosphatasesIBA 07/2012 - 09/2010
2	Estradiol (Delestrogen)FDA LinkGeneric 05/2008 - 04/2006
2	EnzymesIBA 04/2008 - 02/2006
1	Docetaxel (Taxotere)FDA Link 01/2021
1	ruxolitinibIBA 01/2021
1	fedratinibIBA 01/2021
1	baricitinibIBA 01/2021
1	Janus Kinase 2IBA 01/2021
1	AntigensIBA 01/2020
1	Farnesyltranstransferase (Farnesyltransferase)IBA 10/2019
1	TransferasesIBA 10/2019
1	FendilineIBA 05/2019
1	L-Type Calcium Channels (Dihydropyridine Receptor)IBA 05/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphateIBA 01/2019
1	GSK 1363089IBA 01/2019
1	cabozantinibIBA 01/2019
1	Glycogen Synthase Kinase 3IBA 12/2018
1	CateninsIBA 12/2018
1	abirateroneIBA 12/2018
1	UbiquitinIBA 01/2018
1	VemurafenibIBA 01/2018
1	dabrafenibIBA 01/2018
1	Phenobarbital (Luminal)FDA Link 01/2018
1	Tyrosine (L-Tyrosine)FDA Link 01/2018
1	adavosertibIBA 01/2017
1	ProteomeIBA 01/2017
1	(+)-JQ1 compoundIBA 01/2017
1	BI 2536IBA 01/2017
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2016
1	ErbB Receptors (EGF Receptor)IBA 03/2015
1	Estrogen ReceptorsIBA 10/2014
1	Tamoxifen FDA LinkGeneric 10/2014
1	Estrogens (Estrogen)FDA Link 10/2014
1	Selective Estrogen Receptor Modulators (SERM)IBA 10/2014
1	Dasatinib (BMS 354825)FDA Link 10/2014
1	Histone DemethylasesIBA 10/2014
1	PI-1840IBA 04/2014
1	Bortezomib (Velcade)FDA Link 04/2014
1	ARQ 197IBA 02/2014
1	Matrix Metalloproteinases (MMPs)IBA 03/2013
1	Interferon alpha-2 (Roferon-A)FDA Link 07/2012
1	Pharmaceutical PreparationsIBA 09/2010
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2010
1	PI 083IBA 08/2010
1	Complementary DNA (cDNA)IBA 05/2008
1	3 (or 17)-beta-hydroxysteroid dehydrogenaseIBA 05/2008
1	2- ethyl- 16- ((3- pyridylmethylamino)carbonylmethyl)estroneIBA 05/2008
1	NSC 74859IBA 05/2007

Therapy/Procedure

9	Therapeutics 01/2021 - 05/2008
5	Castration 01/2022 - 06/2012
1	Radiotherapy 12/2018
1	Cell Transplantation 11/2017
1	Drug Therapy (Chemotherapy) 01/2017